Seattle Labs is offering free anti-junkmail tool designed to consolidate and manage the disparate lists of known spammers. Blacklist Wizard works with any email server product, and filters spam by refusing it at the server level.
The company's press release says there are many different spammer lists currently operating, "but they are all in different formats, and there has been no central facility for coordinating and managing them." Blacklist Wizard currently imports seven different formats of lists (with more to come), and allows users to combine them, eliminate duplicates, and export the list in a common format to an email server.
The Seattle Labs site also offers a compendium of blacklists.