"Anti-aging drugs, once a sci-fi pipe dream, are now the subject of serious scientific inquiry. Within the next decade, people may slow their biological clocks simply by taking a pill. (((SLOW them? The real money's in *reversing* them.)))
"So what's that pill going to cost? Will it follow a precedent set by $100,000-a-year cancer drugs? Could long, healthy lives become the privilege of the wealthy, with the poor consigned to disease and slow death? (((What, you mean like the USA? Oh wait.)))
"Yesterday we covered a study, published today in Nature, in which diabetic mice were successfully treated with a drug that activates the SIRT1 enzyme. SIRT1 belongs to a family of enzymes called sirtuins that regulate cellular function, and is closely tied to mitochondrial rejuvenation.
"Mitochondria are present in every cell in our body, busily converting glucose to chemical energy – a process that releases DNA-damaging free radicals. As damage accumulates, mitochondria malfunction and tissue fails. Some scientists think that mitochondrial degeneration underlies heart disease, diabetes, cancer, Parkinson's, Alzheimer's and a host of other disorders. These conditions, they say, fall into a single class:
disease of aging.
"It's a controversial proposition, but it's not crazy...."